On my ride home last night, I had a cyclist mention the brightness of my lights and then at a later stop light, I had a passenger in the car next to me roll down their window and ask about the lights I use. While the first time I've had someone in a car ask or say anything, I get comments from other cyclists and pedestrians semi-regularly. Which, on the one hand, is good. It means that the light setup I'm using is very visible. On the other hand, it means that many other cyclists are less visible. Good lights make a huge difference both for seeing and being seen.
Oh, and for reference, my normal lighting strategy includes the following lights: